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  • D-saccharic acid-1,4-lactone ameliorates alloxan-induced diabetes mellitus and oxidative stress in rats through inhibiting pancreatic beta-cells from apoptosis via mitochondrial dependent pathway.

D-saccharic acid-1,4-lactone ameliorates alloxan-induced diabetes mellitus and oxidative stress in rats through inhibiting pancreatic beta-cells from apoptosis via mitochondrial dependent pathway.

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2011 Dec 1 Others Fist_Author_Year_PM

Full Author : ['Bhattacharya, Semantee', 'Manna, Prasenjit', 'Gachhui, Ratan', 'Sil, Parames C']
Journal Title : Toxicology and applied pharmacology
Chapter : Section3
Journal Year : 2011
Cited by : Not Available

Oxidative stress plays a vital role in diabetic complications. To suppress the oxidative stress mediated damage in diabetic pathophysiology, a special focus has been given on naturally occurring antioxidants present in normal diet. D-saccharic acid 1,4-la.....

Keywords : ["dsaccharic ameliorate alloxaninduce diabetes mellitus", "apoptosis via mitochondrial dependent pathway", "inhibit pancreatic betacell", "oxidative stress", "rat"]