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  • Design, synthesis and in-vivo hypoglycemic evaluation of novel non - TZD'S in a type - 2 diabetic model.

Design, synthesis and in-vivo hypoglycemic evaluation of novel non - TZD'S in a type - 2 diabetic model.

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2013 Feb Others Fist_Author_Year_PM

Full Author : ['Jadhav, Rupali', 'Gupta-Rajoria, Ranu', 'Pal, Tanushree', 'Subramanian, Ramaa Chelakara']
Journal Title : Medicinal chemistry (Shariqah (United Arab Emirates))
Chapter : Section3
Journal Year : 2013
Cited by : Not Available

With a view to develop novel non-TZD anti-diabetic compounds, series of isoxazolidinediones were designed to target the PPAR-gamma receptors. Docking studies were performed on co-crystallized protein structure of rosiglitazone with PPAR-gamma receptor obt.....

Keywords : ["type diabetic model", "novel non tzds", "invivo hypoglycemic evaluation", "design synthesis"]