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- Chronic DPP-IV inhibition with PKF-275-055 attenuates inflammation and improves gene expressions responsible for insulin secretion in streptozotocin induced diabetic rats.
Full Author : ['Akarte, Atul Sureshrao', 'Srinivasan, B P', 'Gandhi, Sonia', 'Sole, Sushant']
Journal Title : European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
Chapter : Section3
Journal Year : 2012
Cited by : Not Available
Inhibitors of dipeptidyl peptidase-4 (DPP-IV), a key regulator of the actions of incretin hormones, exert antihyperglycemic effects in type 2 diabetic patients. A major question concerns the potential ability of long term DPP-IV inhibition to have benefic.....
Keywords : ["streptozotocin induce diabetic rat", "improve gene expression responsible", "chronic dppiv inhibition", "insulin secretion", "attenuate inflammation"]