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  • Synthesis, characterization and biological evaluation of some novel 2,4-thiazolidinediones as potential cytotoxic, antimicrobial and antihyperglycemic agents.

Synthesis, characterization and biological evaluation of some novel 2,4-thiazolidinediones as potential cytotoxic, antimicrobial and antihyperglycemic agents.

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2012 Oct 15 Others Fist_Author_Year_PM

Full Author : ['Avupati, Vasudeva Rao', 'Yejella, Rajendra Prasad', 'Akula, Annapurna', 'Guntuku, Girija Sankar', 'Doddi, Bhagya Raju', 'Vutla, Venkata Rao', 'Anagani, Suvarna Ratna', 'Adimulam, Lakshmana Santhi', 'Vyricharla, Aruna Kumar']
Journal Title : Bioorganic & medicinal chemistry letters
Chapter : Section3
Journal Year : 2012
Cited by : Not Available

A series of some novel 2,4-thiazolidinediones (TZDs) (2a-x) have been synthesized and characterized by FTIR, (1)H NMR, (13)C NMR and LC mass spectral analysis. All the synthesized compounds were evaluated for their cytotoxicity, antimicrobial and in vivo .....

Keywords : ["potential cytotoxic antimicrobial", "synthesis characterization", "biological evaluation", "antihyperglycemic agent", "novel"]