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  • Trigonelline ameliorates diabetic hypertensive nephropathy by suppression of oxidative stress in kidney and reduction in renal cell apoptosis and fibrosis in streptozotocin induced neonatal diabetic (nSTZ) rats.

Trigonelline ameliorates diabetic hypertensive nephropathy by suppression of oxidative stress in kidney and reduction in renal cell apoptosis and fibrosis in streptozotocin induced neonatal diabetic (nSTZ) rats.

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2012 Dec Others Fist_Author_Year_PM

Full Author : ['Ghule, Arvindkumar E', 'Jadhav, Suresh S', 'Bodhankar, Subhash L']
Journal Title : International immunopharmacology
Chapter : Section3
Journal Year : 2012
Cited by : Not Available

Oxidative stress and apoptotic cell death in kidney have been suggested as contributing factors in the development and complication of diabetes especially in diabetic nephropathy (DN). This study investigated the effects of trigonelline (TG) on the renal .....

Keywords : ["streptozotocin induce neonatal diabetic nstz rat", "trigonelline ameliorate diabetic hypertensive nephropathy", "renal cell apoptosis", "oxidative stress", "suppression", "reduction", "kidney", "fibrosis"]