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  • Doxorubicin treatment inhibits PPARgamma and may induce lipotoxicity by mimicking a type 2 diabetes-like condition in rodent models.

Doxorubicin treatment inhibits PPARgamma and may induce lipotoxicity by mimicking a type 2 diabetes-like condition in rodent models.

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2013 Jan 16 Others Fist_Author_Year_PM

Full Author : ['Arunachalam, Sankarganesh', 'Tirupathi Pichiah, P B', 'Achiraman, Shanmugam']
Journal Title : FEBS letters
Chapter : Section3
Journal Year : 2013
Cited by : Not Available

Doxorubicin-treated animals show elevated serum triglyceride and blood glucose levels. Adipocytes play an important role in buffering blood glucose and lipids. A raise in serum lipid level triggers adipogenesis in order to increase the lipid absorption ca.....

Keywords : ["doxorubicin treatment inhibit ppargamma", "type diabeteslike condition", "may induce lipotoxicity", "rodent model", "mimic"]