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  • D-saccharic acid 1,4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via NF-kappaB and PKC signaling.

D-saccharic acid 1,4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via NF-kappaB and PKC signaling.

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2013 Feb 15 Others Fist_Author_Year_PM

Full Author : ['Bhattacharya, Semantee', 'Manna, Prasenjit', 'Gachhui, Ratan', 'Sil, Parames C']
Journal Title : Toxicology and applied pharmacology
Chapter : Section3
Journal Year : 2013
Cited by : Not Available

Increasing evidence suggests that oxidative stress is involved in the pathogenesis of diabetic nephropathy (DN) and this can be attenuated by antioxidants. D-Saccharic acid 1,4-lactone (DSL) is known for its detoxifying and antioxidant properties. Our ear.....

Keywords : ["dsaccharic acid protect diabetic rat kidney", "renal inflammatory cytokine via nfkappab", "ameliorate hyperglycemiamediated oxidative stress", "pkc signaling"]