Proteome wide reduction in AGE modification in streptozotocin induced diabetic mice by hydralazine mediated transglycation.
The non-enzymatic reaction between glucose and protein can be chemically reversed by transglycation. Here we report the transglycation activity of hydralazine using a newly developed MALDI-TOF-MS based assay. Hydralazine mediated transglycation of HbA1c, .....