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  • Glycoxidative damage to human DNA: Neo-antigenic epitopes on DNA molecule could be a possible reason for autoimmune response in type 1 diabetes.

Glycoxidative damage to human DNA: Neo-antigenic epitopes on DNA molecule could be a possible reason for autoimmune response in type 1 diabetes.

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2014 Mar Others Fist_Author_Year_PM

Full Author : ['Ahmad, Saheem', 'Moinuddin', 'Shahab, Uzma', 'Habib, Safia', 'Salman Khan, M', 'Alam, Khursheed', 'Ali, Asif']
Journal Title : Glycobiology
Chapter : Section3
Journal Year : 2014
Cited by : Not Available

Advanced glycation end-products (AGEs) are known to be mutagenic, diabetogenic and vascular disease risk factors. Methylglyoxal (MG) is a dicarbonyl species that reacts with biological macromolecule (proteins, DNA and lipids) to give AGEs. Nonenzymatic gl.....

Keywords : ["human dna neoantigenic epitope", "dna molecule could", "type diabetes", "possible reason", "glycoxidative damage", "autoimmune response"]