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  • Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: study in juvenile diabetic rat.

Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: study in juvenile diabetic rat.

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2014 Apr 25 Others Fist_Author_Year_PM

Full Author : ['Khan, S', 'Jena, G B']
Journal Title : Chemico-biological interactions
Chapter : Section3
Journal Year : 2014
Cited by : Not Available

Type 1 diabetes (T1D) also known as juvenile diabetes is a chronic autoimmune disorder that precipitates in genetically susceptible individuals by environmental factors particularly during early age. Both genetic and epigenetic factors are implicated in t.....

Keywords : ["juvenile diabetic rat", "betacell proliferation function", "apoptotic pathway study", "sodium butyrate", "protective role", "hdac inhibitor", "glucose homeostasis", "modulation", "mapk"]