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  • Strategies for preclinical pharmacokinetic investigation in streptozotocin-induced diabetes mellitus (DMIS) and alloxan-induced diabetes mellitus (DMIA) rat models: case studies and perspectives.

Strategies for preclinical pharmacokinetic investigation in streptozotocin-induced diabetes mellitus (DMIS) and alloxan-induced diabetes mellitus (DMIA) rat models: case studies and perspectives.

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2015 Mar Others Fist_Author_Year_PM

Full Author : ['Srinivas, Nuggehally R']
Journal Title : European journal of drug metabolism and pharmacokinetics
Chapter : Section3
Journal Year : 2015
Cited by : Not Available

Preclinical rodent models that manifest type 2 diatetes mellitus using either streptozotocin (DMIS) or alloxan (DMIA) have been well established. Both DMIS and DMIA models have served as key experimental tools to evaluate and understand the pharmacokineti.....

Keywords : ["alloxaninduce diabetes mellitus dmia rat model case study", "streptozotocininduce diabetes mellitus dmis", "preclinical pharmacokinetic investigation", "strategy", "perspective"]