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  • Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-beta1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats.

Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-beta1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats.

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2014 Nov Others Fist_Author_Year_PM

Full Author : ['Khan, Sabbir', 'Jena, Gopabandhu']
Journal Title : Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Chapter : Section3
Journal Year : 2014
Cited by : Not Available

Recent reports highlighted the role of histone deacetylases (HDACs) in the pathogenesis of diabetic nephropathy (DN), but the exact molecular mechanisms by which HDAC inhibitors ameliorate DN still remain unclear. The present study was aimed to investigat.....

Keywords : ["hdac inhibitor ameliorate eno ino", "juvenile diabetic rat", "sodium butyrate", "fibrogenesis apoptosis", "dna damage", "kidney"]