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  • Gallic acid attenuates high-fat diet fed-streptozotocin-induced insulin resistance via partial agonism of PPARgamma in experimental type 2 diabetic rats and enhances glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway.

Gallic acid attenuates high-fat diet fed-streptozotocin-induced insulin resistance via partial agonism of PPARgamma in experimental type 2 diabetic rats and enhances glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway.

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2014 Dec 15 Others Fist_Author_Year_PM

Full Author : ['Gandhi, Gopalsamy Rajiv', 'Jothi, Gnanasekaran', 'Antony, Poovathumkal James', 'Balakrishna, Kedike', 'Paulraj, Michael Gabriel', 'Ignacimuthu, Savarimuthu', 'Stalin, Antony', 'Al-Dhabi, Naif Abdullah']
Journal Title : European journal of pharmacology
Chapter : Section3
Journal Year : 2014
Cited by : Not Available

In this study, the therapeutic efficacy of gallic acid from Cyamopsis tetragonoloba (L.) Taub. (Fabaceae) beans was examined against high-fat diet fed-streptozotocin-induced experimental type 2 diabetic rats. Molecular-dockings were done to determine the .....

Keywords : ["gallic acid attenuate highfat diet fedstreptozotocininduce insulin resistance via partial agonism", "experimental type diabetic rat", "enhance glucose uptake", "signal pathway", "translocation", "ppargamma", "activation"]