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  • 4-Hydroxyisoleucine improves insulin resistance by promoting mitochondrial biogenesis and act through AMPK and Akt dependent pathway.

4-Hydroxyisoleucine improves insulin resistance by promoting mitochondrial biogenesis and act through AMPK and Akt dependent pathway.

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2014 Dec Others Fist_Author_Year_PM

Full Author : ['Rawat, Arun Kumar', 'Korthikunta, Venkateswarlu', 'Gautam, Sudeep', 'Pal, Savita', 'Tadigoppula, Narender', 'Tamrakar, Akhilesh Kumar', 'Srivastava, Arvind Kumar']
Journal Title : Fitoterapia
Chapter : Section3
Journal Year : 2014
Cited by : Not Available

4-Hydroxyisoleucine (4-HIL) is an unusual amino acid isolated from fenugreek seeds (Trigonella foenum graecum L). Various studies have shown that it acts as an antidiabetic agent yet its mechanism of action is not clear. We therefore investigated the effe.....

Keywords : ["promote mitochondrial biogenesis", "improve insulin resistance", "akt dependent pathway", "ampk", "act"]