Design, Synthesis, and Biological Evaluation of Thiazolidine-2,4-dione Conjugates as PPAR-gamma Agonists.
A library of synthesized conjugates of phenoxy acetic acid and thiazolidinedione 5a-m showed potent peroxisome proliferator activated receptor-gamma (PPAR-gamma) transactivation as well as significant blood glucose lowering effect comparable to the standa.....