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  • Rufinamide Improves Functional and Behavioral Deficits via Blockade of Tetrodotoxin-Resistant Sodium Channels in Diabetic Neuropathy.

Rufinamide Improves Functional and Behavioral Deficits via Blockade of Tetrodotoxin-Resistant Sodium Channels in Diabetic Neuropathy.

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2015 Others Fist_Author_Year_PM

Full Author : ['Kharatmal, Shivsharan B', 'Singh, Jitendra N', 'Sharma, Shyam S']
Journal Title : Current neurovascular research
Chapter : Section3
Journal Year : 2015
Cited by : Not Available

Rufinamide is a structurally novel, antiepileptic drug approved for the treatment of Lennox-Gastaut syndrome. Its mechanism of action involves inhibition of voltage-gated Na+ channels (VGSCs) with possible membrane-stabilizing effects. VGSCs play a signif.....

Keywords : ["behavioral deficit via blockade", "tetrodotoxinresistant sodium channel", "rufinamide improve functional", "diabetic neuropathy"]