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  • Strong inhibition of the polyol pathway diverts glucose flux to protein glycation leading to rapid establishment of secondary complications in diabetes mellitus.

Strong inhibition of the polyol pathway diverts glucose flux to protein glycation leading to rapid establishment of secondary complications in diabetes mellitus.

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2016 Apr Others Fist_Author_Year_PM

Full Author : ['Jagdale, Ashwini D', 'Bavkar, Laxman N', 'More, Tanaji A', 'Joglekar, Madhav M', 'Arvindekar, Akalpita U']
Journal Title : Journal of diabetes and its complications
Chapter : Section3
Journal Year : 2016
Cited by : Not Available

BACKGROUND: Polyol pathway and protein glycation are implicated in establishing secondary complications in diabetes. Their relative contribution to the process needs to be evaluated. It is essential to understand why some aldose reductase inhibitors (ARIs.....

Keywords : ["polyol pathway divert glucose flux", "protein glycation lead", "strong inhibition", "secondary complication", "rapid establishment", "diabetes mellitus"]