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  • A murine model of type 2 diabetes mellitus developed using a combination of high fat diet and multiple low doses of streptozotocin treatment mimics the metabolic characteristics of type 2 diabetes mellitus in humans.

A murine model of type 2 diabetes mellitus developed using a combination of high fat diet and multiple low doses of streptozotocin treatment mimics the metabolic characteristics of type 2 diabetes mellitus in humans.

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2017 Mar-Apr Others Fist_Author_Year_PM

Full Author : ['Nath, Sayantan', 'Ghosh, Sankar Kumar', 'Choudhury, Yashmin']
Journal Title : Journal of pharmacological and toxicological methods
Chapter : Section3
Journal Year : 2017
Cited by : Not Available

INTRODUCTION: A murine model of type 2 diabetes mellitus was used to compare the antidiabetic effects of the dipeptidyl peptidase-4 (DPP4) inhibitor vildagliptin and biguanide, metformin. METHODS: Swiss albino mice (n=20 males; n=25 females) were given hi.....

Keywords : ["type diabetes mellitus develop use", "type diabetes mellitus", "streptozotocin treatment mimic", "multiple low dose", "high fat diet", "murine model", "metabolic characteristic", "human", "combination"]