Peroxisome Proliferated Activated Receptors (PPARs): Opportunities and Challenges for Ocular Therapy.
Peroxisome proliferator-activated receptors (PPARs) are nuclear transcription factors. They exist in three isoforms (PPAR-alpha, PPAR-beta/delta, and PPAR-Upsilon) in humans, but mainly PPAR-Upsilon, and they are expressed in retinal epithelial pigment. P.....